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. 2010 Oct 14;1:116. doi: 10.3389/fphar.2010.00116

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Copyright © 2010 Zhang, Gong and Yu.

This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.

PMC Copyright notice

Prostanoid biosynthesis and response pathway. AA, arachidonic acid; PLA₂, phospholipase A₂; PGHS1/2, prostaglandin G/H synthase 1 or 2, which contains both cyclooxygenases (COX) and peroxidase (POX) activities; PGIS, prostaglandin I₂ synthase; PGES, prostaglandin E₂ synthase; PGFS, prostaglandin F synthase; PGDS, prostaglandin D₂ synthase; TxS, thromboxane A₂ synthase; IP, prostaglandin I₂ receptor; EP, prostaglandin E₂ receptor; FP, prostaglandin F_2α receptor; DP, prostaglandin D₂ receptor; TP, thromboxane A₂ receptor.