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Patient cohort diagnosis, treatment and follow-up. A total of 112 HIV-positive patients with acute hepatitis C virus (HCV) were recruited to the the St Mary's Acute HCV Cohort study of whom 17 spontaneously cleared HCV. Treatment with pegylated interferon α (IFNα) and ribavirin was given for 48 weeks to 62 patients and withheld or delayed in a further 26. The sustained virological response rate was 66%. Ab, antibody; LFTs, liver function tests; RT-PCR, reverse transcription–PCR.
