Table 6.
Change in matrix metallopeptidase gene expression in human tendinopathy
| Gene Symbol | Description | p-value | q-value | Fold Change | |
|---|---|---|---|---|---|
| Regulated | |||||
| MMP2 | Matrix metallopeptidase 2 | Expressed | 7.42E-03 | 4.82E-02 | 1.8 |
| MMP3 | Matrix metallopeptidase 3 | Expressed | 5.50E-02 | 2.38E-01 | 0.3 |
| MMP14 | Matrix metallopeptidase 14 | Expressed | 1.79E-03 | 1.66E-02 | 1.9 |
| MMP19 | Matrix metallopeptidase 19 | Expressed | 1.91E-03 | 1.66E-02 | 3.4 |
| Not Regulated | |||||
| MMP28 | Matrix metallopeptidase 28 | Expressed | 0.09 | 0.30 | 1.4 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | Expressed | 0.10 | 0.30 | 1.6 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | Expressed | 0.37 | 0.50 | 1.1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | Expressed | 0.26 | 0.49 | 0.9 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | Expressed | 0.71 | 0.80 | 0.9 |
| Expressed below limited of detection | |||||
| MMP1 | Matrix metallopeptidase 1 | - | 0.96 | 0.96 | 1.0 |
| MMP7 | Matrix metallopeptidase 7 | - | 0.34 | 0.49 | 0.8 |
| MMP8 | Matrix metallopeptidase 8 | - | 0.81 | 0.84 | 0.8 |
| MMP9 | Matrix metallopeptidase 9 | - | 0.00 | 0.02 | 3.2 |
| MMP10 | Matrix metallopeptidase 10 | - | 0.08 | 0.30 | 0.8 |
| MMP12 | Matrix metallopeptidase 12 | - | 0.79 | 0.84 | 0.9 |
| MMP13 | Matrix metallopeptidase 13 | - | 0.03 | 0.14 | 2.6 |
| MMP15 | Matrix metallopeptidase 15 | - | 0.15 | 0.35 | 0.5 |
| MMP16 | Matrix metallopeptidase 16 | - | 0.57 | 0.67 | 0.6 |
| MMP17 | Matrix metallopeptidase 17 | - | 0.56 | 0.67 | 0.8 |
| MMP20 | Matrix metallopeptidase 20 | - | 0.53 | 0.67 | 0.7 |
| MMP21 | Matrix metallopeptidase 21 | - | 0.13 | 0.33 | 1.5 |
| MMP23A/B | Matrix metallopeptidase 23A/B | - | 0.34 | 0.49 | 0.8 |
| MMP24 | Matrix metallopeptidase 2 | - | 0.29 | 0.49 | 0.6 |
| MMP25 | Matrix metallopeptidase 25 | - | 0.18 | 0.40 | 0.7 |
| MMP26 | Matrix metallopeptidase 26 | - | 0.34 | 0.49 | 0.8 |
| MMP27 | Matrix metallopeptidase 27 | - | 0.33 | 0.49 | 0.8 |