Table 2. Allele frequencies and association with prostate cancer for significant EphB2 SNPs.
dbSNP ID | Position (bp) | Gene Region | Allele | Cases | Controls | OR | 95%CI | P-value |
rs4263970 | 22936517 | Intron 1 | A | 0.51 | 0.42 | 1.31 | 1.16–1.90 | 0.001 |
rs1318720 | 22939099 | Intron 1 | G | 0.26 | 0.35 | 0.70 | 0.54–0.92 | 0.001 |
rs4612601 | 22939631 | Intron 1 | G | 0.56 | 0.47 | 1.35 | 1.18–1.92 | 0.001 |
TGEN-624 | 22983969 | - | A | 0.01 | 0.05 | 0.22 | 0.08–0.66 | 1×10−5 |
rs10465531 | 23006379 | Intron 3 | A | 0.15 | 0.22 | 0.71 | 0.51–0.94 | 0.004 |
rs10465543 | 23006805 | Intron 3 | A | 0.15 | 0.23 | 0.49 | 0.36–0.74 | 0.0001 |
rs12090415 | 23027818 | Intron 3 | A | 0.30 | 0.40 | 0.70 | 0.59–0.93 | 0.0001 |
OR [95% CI] and P-value adjusted for age and West African ancestry.
Chromosome positions according to Build 36, hg18.