Fig. 1.
(A) Average daily consumption (g/kg) of 5% alcohol solution in DAT homozygote (-/-), heterozygote (+/-) and wildtype (+/+) littermate mice. All mice were tested in the schedule-induced polydipsia paradigm for 40 minutes each day. Results showed that g/kg alcohol consumption in DAT-/- and DAT+/- mice was, respectively, significantly less than or greater then that of DAT+/+ mice. (B) Alcohol consumption (g/kg) averaged over the 10 test days. (C) Blood alcohol concentration (BAC) determined immediately following removal from the test chambers on test day 10. The vertical bar in each figure shows one standard error of the difference (SED) in group means. * significantly different from DAT+/+ (Dunnett's t-test).
