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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Alcohol. 2011 Feb 26;45(4):325–339. doi: 10.1016/j.alcohol.2010.12.006

Fig. 5.

Fig. 5

(A and B) The relationship between DAR sensitivity expressed as mean percentage change in accumbens DA efflux and g/kg alcohol consumption in individual DAT+/- and DAT+/+ mice. The results of 20 and 40 conditioning pulses are shown. In both cases low DAR sensitivity was significantly associated with the largest amount of g/kg alcohol consumption. (C) DAT uptake efficiency at baseline and g/kg alcohol consumption in individual DAT+/- and DAT+/+ mice. (D) DAT capacity following non-maximal maximal DAT blockade with nomifensine (10 mg/kg i.p.) and g/kg alcohol consumption in individual DAT+/- and DAT+/+ mice. High DAT capacity was significantly associated with high levels of g/kg alcohol consumption. The relationship between DAT efficiency and alcohol consumption approached significance. See Figure 3 and the Methods for additional details.