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. Author manuscript; available in PMC: 2012 Jun 11.
Published in final edited form as: Eur J Pharmacol. 2011 Jan 3;660(1):94–102. doi: 10.1016/j.ejphar.2010.10.113

Fig. 2.

Fig. 2

Effects of MRAP on MC2-like receptor chimeras. (A) Cells were transfected with plasmids encoding receptors and either RAMP3 (Control) or MRAP. Surface receptor is expressed percent of the values obtained with MC2 receptor and MRAP. Points are averaged from 3 to 23 experiments. (B) Cells were transfected with plasmids encoding CRE-luciferase, receptors and either control plasmid or MRAP. The next day cells were incubated with vehicle, 20 µM forskolin or 1 µM ACTH plus 1 µM NDP-α-MSH for 5 h when luciferase activity was measured. Data are expressed relative to the response to forskolin. *P<0.05 vs no MRAP.