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. Author manuscript; available in PMC: 2012 Jun 11.
Published in final edited form as: Eur J Pharmacol. 2011 Jan 1;660(1):80–87. doi: 10.1016/j.ejphar.2010.10.101

Figure 8.

Figure 8

Effect of SHU9119 on food intake (mean ± S.E.M.) in satiated wild type, MC4KO, and MC3KO littermate mice (n=10–12 per group). A) In the wild type mice the 1.0 and 3.0 nmol dose statistically increased food intake relative to saline starting at t=7h and t= 5h, respectively, and continued to remain statistically significant up to the 24h post injection time point (*p<0.05). B) In the MC4KO and MC3KO mice, no statistically significant changes in food intake relative to saline was observed.