Table 1. Outcome metric values for the test/retest data (n = 6) using VT with 120 minutes scan duration.
The mean and standard deviations across all subjects and all regions (listed in Figure 3, with the exception of the cerebellum) is shown. The model that attained the best result in each category is bolded. 2TC: two-tissue compartment; 2TCC: two-tissue compartment constrained; LEGA: likelihood estimation in graphical analysis; 2TCNI: two-tissue compartment non-iterative; PD: percent difference; WSMSS: within subject mean sum of squares; ICC: intraclass correlation coefficient; ID: identifiability
| 2TC | 2TCC | 2TCNI | Logan | LEGA | |
|---|---|---|---|---|---|
| PD (%) | 5.92 ± 4.13 | 6.84 ± 4.40 | 6.36 ± 4.65 | 8.19 ± 4.35 | 7.72 ± 4.17 |
| WSMSS (mL/cc)2 | 0.08 ± 0.03 | 0.10 ± 0.03 | 0.09 ± 0.05 | 0.14 ± 0.06 | 0.13 ± 0.06 |
| ICC (unitless) | 0.87 ± 0.08 | 0.84 ± 0.09 | 0.83 ± 0.11 | 0.77 ± 0.15 | 0.79 ± 0.13 |
| Variance (mL/cc) | 0.55 ± 0.18 | 0.55 ± 0.17 | 0.55 ± 0.19 | 0.58 ± 0.18 | 0.61 ± 0.20 |
| ID (mL/cc) | 1.11 ± 0.46 | 1.18 ± 0.45 | 1.09 ± 0.39 | 1.17 ± 0.38 | 1.08 ± 0.32 |