Table 3.
Associations between continuous 6-month Hollingshead scores and standardized CANTAB and WJTA outcomes with analysis of mediation
| Outcomes | Regression β-coefficient (95% CI)1 |
Mediation test: % of association explained by mediator (p value)1 |
||
|---|---|---|---|---|
| 6-month Hollingshead2 | 6-month Hollingshead3 | mediation by 107-month Hollingshead | mediation by 17-year Hollingshead | |
| CANTAB learning/reverse learning outcomes | ||||
| log (IED total trials) | −0.004 (−0.012, 0.004) | 0.001 (−0.009, 0.011) | 39.2% (0.66) | 86.6% (0.06) |
| log (IED pre-ED errors) | −0.008 (−0.016, 0) | −0.006 (−0.016, 0.004) | 19.1% (0.70) | 3.4% (0.89) |
| log (PAL total errors + 1) | −0.008 (−0.016, 0) | −0.004 (−0.014, 0.006) | 14.4% (0.75) | 37.9% (0.10) |
| PAL stages completed | 0.009 (0.001, 0.017) | 0.004 (−0.006, 0.014) | 31.1% (0.45) | 29.2% (0.17) |
| CANTAB attention outcomes | ||||
| log (RTI simple reaction time) | −0.002 (−0.01, 0.006) | −0.001 (−0.011, 0.009) | 109.1% (0.49) | 148.9% (0.07) |
| RVP total misses | −0.011 (−0.02,−0.005) | −0.004 (−0.014, 0.006) | 20.0% (0.56) | 45.5% (0.01) |
| Log (RVP total false alarms + 1) | −0.006 (−0.014, 0.002) | −0.008 (−0.018, 0.002) | 17.4% (0.77) | 1.9% (0.95) |
| CANTAB memory outcomes | ||||
| DMS, % correct (12,000-ms delay) | 0.01 (0.004, 0.016) | 0.009 (−0.001, 0.019) | 1.1% (0.98) | 10.0% (0.62) |
| PRM, % correct | 0.007 (−0.001, 0.015) | 0.004 (−0.006, 0.014) | 18.0% (0.75) | 62.4% (0.03) |
| SRM, % correct | 0.011 (0.005, 0.017) | 0.012 (0.002, 0.022) | 13.4% (0.70) | 6.0% (0.73) |
| Sqrt (SWM within errors) | −0.003 (−0.011, 0.005) | 0.005 (−0.005, 0.015) | 288.5% (0.03) | 27.2% (0.68) |
| Sqrt (SWM total errors) | −0.012 (−0.02, −0.006) | −0.012 (−0.022,−0.002) | 5.2% (0.87) | 5.9% (0.71) |
| WJTA outcomes | ||||
| Passage comprehension | 0.018 (0.01, 0.026) | 0.008 (−0.004, 0.02) | 14.7% (0.50) | 41.4% (0.0004) |
| Calculation | 0.02 (0.014, 0.026) | 0.015 (0.005, 0.025) | 6.7% (0.71) | 21.3% (0.02) |
| Letter-word identification | 0.016 (0.008, 0.024) | 0.012 (0.002, 0.022) | 10.2% (0.66) | 40.0% (0.001) |
| Applied problems | 0.02 (0.014, 0.026) | 0.014 (0.004, 0.024) | 4.2% (0.83) | 32.0% (0.002) |
| Math fluency | 0.018 (0.012, 0.024) | 0.02 (0.01, 0.03) | 30.9% (0.12) | 19.8% (0.06) |
Figures in parentheses are 95% CI.
1
Bold font indicates significance at the 0.05 level.
2
Adjusting for child's sex and color blindness.
3
Adjusting for child's sex, color blindness, 107-month, and 17-year maternal Hollingshead score.