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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Trends Microbiol. 2011 Feb 15;19(4):174–183. doi: 10.1016/j.tim.2011.01.003

Figure 2. Schematic illustration of interaction of cellular proteins with HAdv5 E1A proteins.

Figure 2

The functional consequences of such protein interactions are also indicated. The N-terminal region of E1A exhibits a dominant oncogenic activity while the C-terminal region contributes suppression of oncogenesis. The green upward arrows indicate activation of various cellular processes and the red downward arrows indicate suppression of such processes.