Table 3.
Significant metabolic differences in the liver lipids of ethanol-fed rats obtained from 31P NMR at p ≤ 0.05.
| Location Number |
Chemical Shift Bins (ppm) |
Metabolites | Changea (%) |
|---|---|---|---|
| 1 | 0.36, 0.38, 0.39, 0.40 | Phosphatidylethanol | +33, +37, +57, +63 |
| 2 | 0.50, 0.51–0.70 | Phosphatidylcholine | −35, −51, −59, −60, −66, −71, −69, −68, −71, −75, −73, −71, −70, −65, −62, −64, −60, −50, −55, −55, −42 |
| 3 | 1.09–1.13, 1.14 | Lyso-phosphatidylcholine | +52, +59, +45, +47, +58, +46 |
| 4,5 | 1.34 | Sphingomyelin/ Phosphatidylserine | +22 |
| 6 | 1.52 | Phosphatidylethanolamine | +25 |
| 7 | 1.90–1.98 | Lyso-phosphatidylethanolamine | +96, +147, +144, +228, +272, +218, +140, +167, +260 |
a
The percentage (%) changes were calculated by taking the average bin integration value of control and ethanol-fed animals at each ppm. Bold chemical shift bins correspond to p ≤ 0.01.