Table 2.
Genes differentially regulated for selected cell functions (p-value ≤ 0.05)
| ORF | Gene | Log 2 expression | ORF | Gene | Log 2 expression | ||
|---|---|---|---|---|---|---|---|
| merodiploid | mutant | merodiploid | mutant | ||||
| Fatty acid utilization | Ribosomal proteins | ||||||
| Rv0974c | accD2 | 1.2 | -0.2 | Rv0056 | rplI | -1.0 | -0.6 |
| Rv1935c | echA13 | 0.9 | -0.2 | Rv0682 | rpsL | -0.9 | -0.9 |
| Rv2486 | echA14 | 1.0 | -0.1 | Rv0700 | rpsJ | -1.4 | -0.5 |
| Rv0456c | echA2 | 1.2 | -0.1 | Rv0701 | rplC | -1.5 | -0.4 |
| Rv3550 | echA20 | 1.1 | 0.2 | Rv0716 | rplE | -1.2 | -0.9 |
| Rv0971c | echA7 | 1.3 | -0.1 | Rv0722 | rpmD | -0.9 | -0.3 |
| Rv3546 | fadA5 | 1.1 | 0.1 | Rv0723 | rplO | -0.7 | -0.2 |
| Rv1715 | fadB3 | 1.0 | -0.1 | Rv2441c | rpmA | -0.9 | -0.5 |
| Rv0099 | fadD10 | 1.2 | 0.0 | Rv3442c | rpsI | -0.9 | -0.2 |
| Rv1550 | fadD11 | 1.0 | 0.2 | Rv3443c | rplM | -1.6 | -0.5 |
| Rv1058 | fadD14 | 1.2 | 0.0 | Rv3458c | rpsD | -0.8 | -0.5 |
| Rv3561 | fadD3 | 0.8 | 0.5 | Rv3460c | rpsM | -1.3 | -0.6 |
| Rv0035 | fadD34 | 1.3 | 0.0 | Rv3461c | rpmJ | -1.4 | -0.6 |
| Rv0214 | fadD4 | 0.8 | -0.2 | Rv3924c | rpmH | -1.2 | -0.7 |
| Rv0551c | fadD8 | 0.9 | 0.0 | ||||
| Rv2590 | fadD9 | 1.3 | -0.5 | Anaerobic respiration | |||
| Rv0972c | fadE12 | 1.4 | -0.1 | Rv0252 | nirB | 0.8 | ndr |
| Rv0975c | fadE13 | 1.3 | ndr | Rv0253 | nirD | 1.1 | ndr |
| Rv3061c | fadE22 | 1.0 | -0.1 | Rv0267 | narU | 1.2 | ndr |
| Rv3505 | fadE27 | 1.0 | 0.0 | Rv1161 | narG | 0.7 | ndr |
| Rv3544c | fadE28 | 0.8 | 0.0 | Rv1163 | narJ | 0.7 | ndr |
| Rv3562 | fadE31 | 1.0 | 0.2 | Rv1164 | narI | 0.6 | ndr |
| Rv3563 | fadE32 | 0.8 | 0.4 | Rv1552 | frdA | 1.2 | ndr |
| Rv3564 | fadE33 | 1.2 | 0.3 | Rv1553 | frdB | 0.8 | ndr |
| Rv0752c | fadE9 | 0.9 | -0.1 | Rv1554 | frdC | 1.1 | ndr |
| Rv1492 | mutA | 1.1 | 0.2 | Rv1736c | narX | 1.1 | ndr |
| Rv1493 | mutB | 1.2 | 0.5 | Rv1737c | narK2 | 1.9 | 0.2 |
| Cell surface molecules | Electron Trpt/Redox | ||||||
| Rv0399c | lpqK | 0.8 | -0.1 | Rv0409 | ackA | 1.0 | 0.2 |
| Rv0405 | pks6 | 1.2 | -0.2 | Rv0886 | fprB | 0.8 | 0.1 |
| Rv0593 | lprL | 1.1 | 0.0 | Rv1620c | cydC | 1.6 | 0.0 |
| Rv0604 | lpqO | 0.8 | -0.1 | Rv1622c | cydB | 2.0 | -0.2 |
| Rv0794c | lpdB | 0.9 | -0.2 | Rv1623c | appC | 1.0 | -0.2 |
| Rv1064c | lpqV | 1.1 | -0.1 | Rv2007c | fdxA | 2.6 | 0.6 |
| Rv1166 | lpqW | 0.8 | 0.0 | Rv3251c | rubA | 0.8 | -0.1 |
| Rv1372 | pks18 | 1.1 | 0.1 | ||||
| Rv1661 | pks7 | 1.3 | -0.2 | ATP synthesis | |||
| Rv1662 | pks8 | 1.0 | 0.2 | Rv1304 | atpB | 0.2 | -0.6 |
| Rv1663 | pks17 | 1.2 | 0.2 | Rv1305 | atpE | 0.2 | -0.4 |
| Rv1664 | pks9 | 1.1 | 0.1 | Rv1306 | atpF | 0.0 | -0.7 |
| Rv1665 | pks11 | 0.7 | 0.2 | Rv1307 | atpH | 0.2 | -0.6 |
| Rv1921c | lppF | 1.4 | 0.2 | Rv1308 | atpA | 0.3 | -0.4 |
| Rv1946c | lppG | 1.0 | 0.1 | Rv1309 | atpG | -0.1 | -0.7 |
| Rv1966 | mce3 | 1.1 | 0.0 | Rv1310 | atpD | 0.3 | -0.4 |
| Rv2270 | lppN | 0.9 | -0.1 | Rv1311 | atpC | 0.2 | -0.4 |
| Rv2330c | lppP | 0.7 | 0.1 | ||||
| Rv2543 | lppA | 0.9 | 0.2 | ndr = not differentially regulated | |||
| Rv2796c | lppV | 0.8 | 0.0 | ||||