Table 1.

Comparison of patient and graft characteristics in patients with and without PES.

	PES (n=16)	No PES (n=36)	P-value
Age (years)
Mean (range)	31 (3-65)	41 (7-63)	0.08
Gender (n)
Male	8	20	0.77
Female	8	16
Weight (kilogram)
Median (range)	66 (13-108)	71 (22-109)	0.44
Diagnosis (n)
Lymphoid malignancy	4	10	1.00
Myeloid malignancy	12	26
Preparative Regimen (n)
Myeloablative	12	24	0.75
Non-myeloablative	4	12
Infused Total TNC × 107/kg
Mean (range)	4.5 (2.7-12.6)	4.8 (2.6-9.6)	0.53
Donor-Recipient HLA-match*
Median match of better matched unit (range)	6/10 (4-8/10)	6/10 (3-9/10)	0.46
Median match of lesser matched unit (range)	5/10 (4-8/10)	5/10 (2-9/10)	0.42
Unit-Unit HLA-match *
Median (range)	6/10 (3-10/10)	5/10 (2-9/10)	0.57
Engrafting Unit TNC × 107/kg **
Mean (range)	2.3 (1.3-5.3)	2.5 (1.4-5.1)	0.51
Donor-Recipient HLA-match of Engrafting unit*/ **
Median (range)	6/10 (4-8/10)	6/10 (2-8/10)	0.90

^*10 allele HLA-A,-B,-C,-DRB1,-DQ match

^**Excludes 2 patients with graft failure in each group and the single patient who was in the “No-PES” group who engrafted with both units.

Abbreviations: PES pre-engraftment syndrome; TNC total nucleated cell; HLA human leucocyte antigen.