TABLE 3.

Genes Up-Regulated in Expanded NK Cells and Associated with Biological Process

Biological Process	Genes Affected
Cell killing	MGEA5, TUBB, PRDX1, NCR3-1, NCR3-2, NCR3-3, GNLY, PTPRC, TUBB2C, IL7R, GIMAP5, CD226 (12 genes)
Growth	NDUFS3, ATP6V0E1, EP300, AFG3L2, CDKN2D, CCDC85B, DDX5, PSRC1, CREB1, PARP1, ICMT, C6orf108, ENO3, TSG101, E4F1, CCNB2, CDKN1B, ENO1-1, EI24, NPM1, PDGFB, PRPF19, UBE2E3-1, UBE2E3-2, OGFR, APBB1, RUVBL2, TAF9, IL7R, ENO1-2, BRD8, SOD1, SOCS2, BCAR1, CDKN2A, CHST11, ING1, VPS54 (38 genes)
Immune system process	LTB, CCR2-1, LIG1, GPX2, MSH6, NDFIP1, CTSC-1, SKAP1, LTB4R, TNFSF12, CCL25, DHX58, IMPDH2, AP2B1, MIF, CCL4, CD276, XRCC5, MAP4K2, CCND3, TUBB, GZMA, EOMES, CD2, CLPTM1, CORO1A, NUP85, CCNB2, CCL8, IFI6, TRIM22, OAS1-1, PDGFB, IGJ, TNFRSF4, PRDX1, CXCL5, PSMB9, CD8B, DCLRE1C, CTSC-2, TAP1, ITGAL, KIR2DS2, NCR3-1, NCR3-2, FYN, NCR3-3, RELB, GPI, TESC, CKLF, ITGA6, YWHAZ-1, IGHG1, KIR2DS1, CDC42-1, TACC3, PTPRC, KIR3DL1, IGKC, CD79A, CDC42-2, CRIP2, LCK, TUBB2C, DDOST, KIR2DL3, IL7R, YWHAZ-2, C5, CD28, BMI1, TAC1, GIMAP5, NKX2-5, SOD1, PRDX3, C1QBP, TNFSF10, AP2S1, NME1, UBASH3A, C3AR1, FCN1, CCR2-2, MBP-1, BCAR1, JAG2, CDKN2A, CD226, CTSC-3, MBP-2, CD19, FCGR2B, LST1, MYH9, CTSS, OAS1-2 (99 genes)