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Summary of HIF-1α and HIF-2α target genes analyzed in this study
| Gene type | Proteins |
|---|---|
| HIF-1α unique | Hexokinase 2, glucosephosphate isomerase, phosphofructokinase, aldoase A, aldolase C, triosephosphate isomerase, glyceraldehyde-3-phosphate dehydrogenase, PGK-1, PGM-1, enolase 1, LDHA |
| HIF-1α and HIF-2α commona | Glucose transporter 1, ADRP, NDRG-1, DMXL-1, IL-6, Carbonic anhydrase XII, filaggrin, ADM, VEGF |
No genes uniquely regulated by HIF-2α have as yet been identified.
