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Systolic blood pressure of female SHR by treatment and time (means ± SEM). Two-way repeated measures ANOVA: treatment-F = 19.6, df = 3, P < .001, age-F = 14.7, df = 9, P < .001, interaction-F = 2.3, df = 27, P < .001. Solid circles: controls (n = 8), solid triangles: ovarectomy-OVX (n = 6), open circles: testosterone treated-T (n = 6), open triangles: ovarectomy and testosterone treatment-OVX+T (n = 7).
