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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Reprod Sci. 2010 Sep 22;17(12):1120–1129. doi: 10.1177/1933719110378344

Figure 6. Model of side-specific gestational membrane prostaglandin response to lipopolysaccharide (LPS) stimulation.

Figure 6

LPS induces cyclooxygenase-2 (COX-2) relative to the side of exposure. We propose that relative abundance (denoted by font size) of prostaglandin species secreted from each side is due to tissue-specific expression of prostaglandin synthase enzymes (PTGES and AKR1C3). The mechanism by which prostaglandin E2 (PGE2) and prostaglandin F2α (PGF2α) are released on the amnion side when only the choriodecidual side is treated is not defined (indicated by a question mark).