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. Author manuscript; available in PMC: 2011 May 17.
Published in final edited form as: Toxicol Pathol. 2010 Dec 21;39(1):240–266. doi: 10.1177/0192623310391680

Figure 1.

Figure 1

Hepatocholangiocarcinoma (HCCC), a primary hepatic tumor containing both neoplastic hepatocellular and neoplastic biliary epithelial elements. (A) Typical trabecular morphology of hepatocellular carcinoma in conjunction with exuberant neoplastic biliary epithelial proliferation. (B) Neoplastic trabeculae are at least 3 cell layers thick and (C) blend proliferating hepatocytes and biliary epithelial cells in the same cords. Metastases of HCCC in the heart (D) and lung (E) contain both proliferating hepatocytes and biliary epithelial cells. H&E.