Table 2.
Incidence of rat and mouse ependymomas.
| Rat ependymomas |
| Ward and Rice (1982) surveyed F344 rats and found that ependymomas comprised 4% of the total brain tumors recorded. |
| Maekawa et al. (1984) surveyed 692 F344/DuCrj and 377 Wistar rats and found no ependymomas diagnosed. |
| Krinke et al. (1985) surveyed 8,960 Sprague-Dawley rats and found 2 ependymomas recorded (2% total brain tumors). |
| Gopinath (1986) surveyed 5,395 Sprague-Dawley rats and found 1 ependymoma recorded in a male rat (1% total brain tumors). |
| Yamate et al. (1987) surveyed 3,410 F344 rats and found 2 ependymomas diagnosed (2% total brain tumors). |
| Giknis and Clifford (2000) surveyed 3,377 Sprague-Dawley rats and found no ependymomas diagnosed. |
| Inveresk/Charles River Edinburgh Background incidences (1998–2009) surveyed 2,437 Sprague-Dawley rats and found 1 ependymoma diagnosed.a |
| Mouse ependymomas |
| Radovsky and Mahler (1999) surveyed 4,894 B6C3F1 mice from the NTP archives and found no ependymomas diagnosed. |
| Fraser (1986) surveyed 75,000 mice from the Edinburgh MRC Neuropathogenesis unit archives (strains: A2G/LacDk, VM/Dk, MB/Dk, PCD, C57BL/FaDk, LM/Dk, MM/Dk, SM/RrDk, BALB/c/LacDk, BRVR/SrDk, C3H/LacDk, BSC/Dk, DBA/2LacDk, NZB/LacDk, RIII/FaDk, VM, MB, IM) and found no ependymomas diagnosed. |
| Mikaelian et al. (2004) surveyed 9,284 mice from the Jackson Lab archives (strains C57BL6/J, 129P3/J, A/J, BALB/cByJ, BALB/cJ, C3H/HeJ, CBA/J, DBA/2J, HRS/J, SJL/L) and found no ependymomas diagnosed. |
| Giknis and Clifford (2000) surveyed 5360 Crl:CD-1 (ICR)BR Mice and found 1 ependymoma recorded in a female (1% total brain tumors). |
| Inveresk/Charles River Edinburgh Background incidences (2002) surveyed 1,851 Crl:CD-1 (ICR)BR Mice and found 1 ependymoma diagnosed.a |
| Charles River Edinburgh Background incidences (2010) surveyed 5,755 Crl:CD-1 (ICR)BR Mice and found 1 ependymoma diagnosed.a |
a
Unpublished data from Inveresk/Charles River Laboratories, Edinburgh, UK.