Table 3.
Immunohistochemical markers for retinal gliosis.
Immunohistochemical marker | Cell of interest | Staining characteristics |
---|---|---|
Glial fibrillary acidic protein (GFAP) | Astrocytes and Müller cells | Positive for reactive Müller cells |
Ionized calcium binding adaptor molecule 1 (Iba-1) | Microglial cells | Negative |
Oligodendrocyte lineage transcription factor 2 (Olig 2) | Oligodendrocytes | Negative |
S100 | Schwann cells and astrocytes | Positive for astrocytes, not cells of interest |
Neuron-specific enolase (NSE) | Neuronal cells | Positive for extracellular optic nerve fibers |
Ki67 | Cell proliferation | Negative |
Vimentin | Mesenchymal cells | Positive for Müller cells only |