Table 1.

Age-Adjusted Mean ± SD or Prevalence of Risk Factors and Medications at Baseline (1984 to 1987)

Variable	Cases (n = 228)	Noncases (n = 849)	p Value (Cases Vs. Noncases)
Age, yrs*	72.2 ± 8.8	69.5 ± 10.6	<0.001
Women, %*	42.5	47.5	0.19
Lifestyle factors, %
Current smoker	12.2	12.2	0.97
Exercise >30×/week	80.3	81.5	0.69
Alcohol daily	44.9	44.2	0.84
Medication use, %
Aspirin	17.2	18.6	0.65
Lipid-lowering drugs	0.4	0.5	0.88
Beta-blockers	14.3	12.2	0.41
Risk factors
Diabetes, %	15.9	12.2	0.13
Hypertension, %	67.0	60.6	0.093
BMI	25.6 ± 3.6	25.0 ± 3.6	0.041
Systolic BP, mm Hg	143 ± 19	139 ± 19	0.005
Diastolic BP, mm Hg	78 ±9	77 ± 9	0.22
Laboratory values
Total cholesterol, mg/dl	223 ± 40	218 ± 40	0.078
HDL, mg/dl†	55 ± 16	59 ± 17	0.006
LDL, mg/dl	141 ± 36	135 ± 36	0.013
Triglycerides, mg/dl†	106 ± 57	99 ± 54	0.10
Fasting plasma glucose, g/dl	106 ± 21	100 ± 21	<0.001
CRP, mg/l†	1.8 ± 1.7	1.6 ± 1.6	0.18
Lp-PLA2, ng/ml†	538 ± 180	494 ± 167	<0.001

^*Unadjusted mean; all others are age-adjusted

^†geometric mean.

BMI = body mass index; BP = blood pressure; CRP = C-reactive protein; HDL = high-density lipoprotein; LDL = low-density lipoprotein; Lp-PLA2 = lipoprotein-associated phospholipase A2; SD = standard deviation.