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. Author manuscript; available in PMC: 2012 May 18.
Published in final edited form as: J Am Chem Soc. 2011 Apr 22;133(19):7577–7584. doi: 10.1021/ja201726q

Table 7.

Synthesis and Reactivity of (tmeda)Pd(Aryl)(CF3) Complexes

graphic file with name nihms-291039-f0034.jpg

Entry Compound Aryl Yield
Aryl–CF3
(80 °C)		 Yield
Aryl–CF3
(23 °C)
1 11a p-FC6H4 81% 78%
2 11b p-CF3C6H4 76%a 52%a
3 11c p-CNC6H4 60% 22%
4 11d p-MeOC6H4 92% 95%
5 11e C6H5 94% 88%
6 11f p-MeC6H4 90% 83%
7 11g m-MeC6H4 95% 95%
8 11h o-MeC6H4 85% 88%
9 11i o-MeOC6H4 90% 99%

These reactions were conducted at 80 °C for 3 h and at 23 °C for 1 h. Reactions were run in duplicate and all of the starting material was consumed. Yields were determined by 19F NMR spectroscopy.

a

At both temperatures, trifluorotoluene was formed in 13% yield.