FIG. 10.

Detection of RPA from whole tissue extracts. Extracts from sample numbers 92 (normal lung tissue), 23 (Neuorendocrine carcinoma) were prepared and incubated with 50 ng of plasmid-digested fragments of platinated (black) or nonplatinated (gray) dsDNA. The combined data from the two samples is also presented. The * indicates P < 0.01 and a statistically significant difference. For the individual analyses the statistical assessment did not reach the threshold for a significant difference; however, the power of the t-test was below the desired power of 0.800 (0.476 for sample 92 and 0.550 for sample 23). Less than desired power indicates a lower chance of detecting a difference when one actually exists, and negative results should be interpreted cautiously.