Figure 6.
Effect of cinnamaldehyde on the Ca2+ channel. Rat aortic rings were preincubated with or without cinnamaldehyde for 10 minutes, and the curves of CaCl2 in Ca2+-free solution containing 10−4 M EGTA and 60 mM KCl were inhibited by cinnamaldehyde (A, #P < 0.01 versus controls, n = 6). Comparison of contraction percentage between the cinnamaldehyde-preincubated and control groups on cumulative concentration-response curves of KCl. The constriction curve of KCl was inhibited by cinnamaldehyde (B, *P < 0.05 versus control, #P < 0.01 versus control, n = 6). Effect of cinnamaldehyde on the transient contraction effect of phenylephrine in Ca2+-free solution containing 10−4 M EGTA. With cinnamaldehyde preincubation for 10 minutes, the contraction effect of phenylephrine in Ca2+-free solution was inhibited by cinnamaldehyde (C, #P < 0.01 versus controls, n = 6).