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. 2010 Feb;26(1):37–48. doi: 10.1089/jop.2009.0074

Table 3. .

Particle Size and Polydispersity Values of Nanoparticles Prepared by Dialysis Method and O/W Emulsion/Solvent Evaporation Method

Drug Dialysis method
O/W emulsion/solvent evaporation method
PLGA 50:50
PLGA 50:50
PLGA 65:35
Particle size (nm) mean ± SEM Polydispersity Particle size (nm) mean ± SEM Polydispersity Particle size (nm) mean ± SEM Polydispersity
DEX 216 ± 4 0.10 204 ± 4 0.057 203 ± 3 0.033
HA 251 ± 3 0.09 226 ± 3 0.040 214 ± 2 0.019
PA 237 ± 6 0.12 183 ± 1 0.047 193 ± 2 0.005

Abbreviations: DEX, dexamethasone; DL, drug loading; HA, hydrocortisone acetate; O/W, oil-in-water; PA, prednisolone acetate; PLGA, polylactide-co-glycolide; SEM, standard error of mean.