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. 2011 Apr 6;31(14):5483–5494. doi: 10.1523/JNEUROSCI.5244-10.2011

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Copyright © 2011 the authors 0270-6474/11/315483-12$15.00/0

This article is freely available online through the J Neurosci Open Choice option.

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Figure 5. — Neurophysiological and histological analysis of Dync1li1^N235Y/N235Y mice. A, Dync1li1^N235Y/N235 have mice a significant reduction of the peak-to-peak amplitude of A-fiber compound action potential in the saphenous nerve compared with wild-type littermates. *p < 0.05. B, QSum plots of the neuronal profile area distribution of neurofilament-immunoreactive neurons (giving rise to large myelinated A-fibers; round symbols) and of peripherin-immunoreactive cells (giving rise to C-fibers; square symbols) in lumbar dorsal root ganglia. The cell profile size in both populations is reduced in Dync1li1^N235Y/N235Y mice compared with wild-type littermates.