Table 2.

Cell profile size distribution in cervical and lumbar DRG for CGRP- and parvalbumin-positive neurons

	Cervical		Lumbar
	Wild type (n = 3)	Dync1li1N235Y/N235Y (n = 4)	Wild type (n = 3)	Dync1li1N235Y/N235Y (n = 3)
Total number of CGRP-positive profile areas measured	239	315	255	389
Mean CGRP cell profile area	459 ± 69 (378–595)	420 ± 27 (383–498)	485 ± 26 (469–502)	435 ± 26 (395–484)
Total number of parvalbumin-positive profile areas measured	264	285	233	339
Mean parvalbumin cell profile area	508 ± 26 (477–559)	477 ± 21 (416–509)	474 ± 7 (418–578)	378 ± 7 (364–388)

For mean ± SEM values, the values in parentheses are ranges.

CGRP: The distribution of the profile areas of cervical CGRP-immunoreactive DRG neurons is significantly different (p < 0.005, Kolmogorov–Smirnov test) between wild-type mice (478 ± 276 μm², mean ± SD; n_cells = 239, n_animals = 3) and Dync1li1^N235Y/N235Y littermates (421 ± 229 μm², mean ± SD; n_cells = 315, n_animals = 4). Data not shown. The distribution of the profile areas of lumbar CGRP-immunoreactive DRG neurons is significantly different (p < 0.005, Kolmogorov–Smirnov test) between wild-type mice (484 ± 280 μm², mean ± SD; n_cells = 255, n_animals = 3) and Dync1li1^N235Y/N235Y littermates (432 ± 254 μm², mean ± SD; n_cells = 389, n_animals = 4). Data not shown.

Parvalbumin: The distribution of the profile areas of cervical parvalbumin-immunoreactive DRG neurons is significantly different (p < 0.001, Kolmogorov–Smirnov test) between wild-type mice (503 ± 260 μm², mean ± SD; n_cells = 264, n_animals = 3) and Dync1li1^N235Y/N235Y littermates (468 ± 282 μm², mean ± SD; n_cells = 285, n_animals = 4). Data not shown. The distribution of the profile areas of lumbar parvalbumin-immunoreactive DRG neurons is significantly different (p < 0.001, Kolmogorov–Smirnov test) between wild-type mice (465 ± 276 μm², mean ± SD; n_cells = 233, n_animals = 3) and Dync1li1^N235Y/N235Y littermates (376 ± 196 μm², mean ± SD; n_cells = 393, n_animals = 4) (Fig. 5D).