. 2011 May 17;6(5):e20120. doi: 10.1371/journal.pone.0020120

Table 1. Clinical Characteristics of PCOS and control subjects.

	Discovery		Replication
	Control(n = 198)	PCOS(n = 335)	Control(n = 306)	PCOS(n = 396)
Age (yr)	32.5 (17.0)	27.0 (11.1)^*	51.0 (23.7)	28.0 (9.0)^*
BMI (kg/m²)	24.7 (5.9)	33.4 (14.7)^*	25.9 (8.3)	34.9 (12.3)^*
Total testosterone (nmol/l)	1.40 (0.94)	2.63 (1.14)^*	1.0 (0.52)	2.43 (1.11)^*
DHEAS (µmol/l)	2.58 (2.04)	5.68 (4.57)^*	3.70 (1.75)	5.72 (3.94)^*
Insulin (pmol/l)	41.4 (39.0)	96.0 (108.0)^*	72.0 (45.0)	126.0 (96.0)^*
Glucose (mmol/l)	4.77 (0.56)	4.77 (0.72)	5.01 (0.68)	4.86 (0.64)
HOMA-IR	0.95 (0.84)	2.01 (2.13)^*	1.58 (0.96)	2.69 (1.83)^*
HOMA-%B	104.1 (57.0)	166.9 (108.8)^*	129.5 (58.3)	196.6 (81.0)^*

*P<0.001 compared to control group. Data are median (interquartile range). In the replication cohort, androgen measurements were available only in the cases and controls recruited by R. S. Legro.

Abbreviations: BMI: body mass index; mFG: modified Ferriman-Gallwey hirsutism score; NA: Data not Available; HOMA-IR, homeostasis model assessment of insulin resistance; HOMA-%B, homeostasis model assessment of beta-cell function (insulin secretion).