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Activity of hepatic PPARα and PPARγ in presence of extra-hepatic EHS tumors. Basal and induced target gene expression for PPARα (A) and PPARγ (B). Induced gene expression in non-tumor controls and tumor-bearing mice as achieved by treatment with Wy-14643 (+Wy) for PPARα activation and troglitazone (+Trog) for PPARγ activation (n = 6–9 per group). * p < 0.05 denotes a significant change in gene expression in control versus tumor groups following ligand activation.
