Figure 2. Four tumor types were characterized in trisomic and euploid NPcis mice.
A, MPNST composed of atypical spindle-shaped cells arranged in fascicles, nuclear pleomorphism indicated by arrow (H&E). B, An MPNST showing S-100 protein-positive cells (Schwann cells, brown cells are stained with the DAB substrate). C, H&E stain of an adrenal tumor. D, A drenal tumors were negative for CD3. E, Lymphoma, H&E. F, T-cell lymphomas were positive for CD3. G, A strocytoma showing an irregular mass of tumor (H&E). H, A strocytoma stained positively with GFAP. Scale bar, 50 μm.