Fig. 5.
Expression of astrocyte mRNAs in the cervical and lumbar spinal cords of ALS mice. (A) The mRNA for GFAP, a marker of astrocytes and astrocytosis. (B) The expression of EAAT2, the astroglial glutamate transporter responsible for the removal of glutamate from the synaptic cleft. Each time point represents the mean of n = 3 mice. * ≤ 0.05, ALS mice spinal cord regions compared with the same regions from WT mice; † ≤ 0.01, ALS mice spinal cord regions compared with the same regions from WT mice; ‡ ≤ 0.05, ALS mice cervical spinal cords compared with ALS mice lumbar spinal cords, ‡‡ ≤ 0.01, ALS mice cervical spinal cords compared with ALS mice lumbar spinal cords.