Table 3.
Lipid/apolipoprotein levels and HDL subpopulations in asymptomatic and symptomatic Carriers.
| Asymptomatic Carriers | Symptomatic Carriers | P | |
|---|---|---|---|
| Total cholesterol (mg/dl) | 187.0 ± 49.6 | 188.8 ± 35.7 | 0.910 |
| Triglycerides (mg/dl) | 95.5 ± 50.2 | 123.7 ± 46.5 | 0.122 |
| Unesterified cholesterol (mg/dl) | 55.7 ± 9.0 | 59.1 ± 13.9 | 0.433 |
| Unesterified/total cholesterol | 0.31 ± 0.05 | 0.32 ± 0.06 | 0.700 |
| LDL-Cholesterol (mg/dl) | 130.5 ± 47.1 | 134.5 ± 30.8 | 0.785 |
| Apolipoprotein B (mg/dl) | 95.4 ± 24.8 | 108.4 ± 26.6 | 0.177 |
| HDL-cholesterol (mg/dl) | 36.5 ± 12.4 | 29.5 ± 8.8 | 0.085 |
| Apolipoprotein A-I (mg/dl) | 97.7 ± 22.7 | 89.7 ± 14.9 | 0.264 |
| Apolipoprotein A-II (mg/dl) | 30.4 ± 6.3 | 28.4 ± 4.0 | 0.308 |
| LpA-I (mg/dl) | 34.8 ± 7.0 | 29.7 ± 10.0 | 0.117 |
| LpA-I:A-II (mg/dl) | 62.9 ± 19.5 | 59.9 ± 13.5 | 0.628 |
| Small HDL (%) | 13.8 ± 6.5 | 14.3 ± 4.7 | 0.811 |
| Medium HDL (%) | 17.3 ± 5.1 | 18.3 ± 5.1 | 0.596 |
| Large HDL (%) | 69.0 ± 10.8 | 67.4 ± 8.3 | 0.653 |
| HDL2 (nm) | 11.3 ± 0.3 | 11.2 ± 0.3 | 0.369 |
| HDL3 (nm) | 8.9 ± 0.4 | 9.0 ± 0.4 | 0.499 |
| Preβ-HDL (%) | 18.1 ± 3.7 | 20.0 ± 4.7 | 0.229 |
| CER (nmol/ml/h) | 34.1 ± 15.2 | 30.3 ± 19.3 | 0.554 |
| LCAT activity (nmol/ml/h) | 26.2 ± 10.8 | 22.4 ± 6.2 | 0.473 |
| LCAT (μg/ml) | 4.14 ± 1.38 | 3.39 ± 1.40 | 0.151 |
Data are expressed as mean ± SD; n = 15 in each group.