Fig. 7.

Rinl-dependent recruitment of Rab5a and Rab22 to the cytoskeleton. (A) myc-tagged Rinl (ΔSH2 and ΔVps9) and GDP-bound Rab5a or Rab22 were co-transfected into COS7 cells. Cells were stained with anti-myc antibodies and visualized by confocal microscopy. Representative images are shown. Scale bar, 25 μm. (B) The distribution of Rab5a and Rab22 was quantified as described in Fig. 5. n > 35; Error bars, s.e.m.