Table 3.
Multiple Linear Regression Analysis Testing the Association Between var2csa Gene Copy Number and Gravidity, Weeks of Pregnancy, Age, Parasitemia, and Anti-VAR2CSA IgG Antibody LevelsH
| Tested parameters | Coeff. | [95% CI] | P value |
| Ngali II n = 55 | |||
| Primi-multigravidae | −.50 | −1.68 to .78 | .474 |
| Weeks of pregnancy | 0.027 | −.013 to .068 | .181 |
| Maternal age | 0.023 | −.079 to .12 | .662 |
| Parasitemia | 0.18 | .050 to .31 | .007 |
| Anti-VAR2CSA DBL4ϵ IgG | 0.38 | .16 to .60 | .001 |
| Cons-* | −.20 | −2.17 to 1.77 | .843 |
| Yaoundé (n=43) | |||
| Primi-multigravidae | 0.58 | −.62 to 1.78 | .341 |
| Weeks of pregnancy | −.037 | −.080 to .0059 | .091 |
| Maternal age | −.0057 | −.13 to .12 | .928 |
| Parasitemia | 0.026 | −.098 to .15 | .682 |
| Anti-VAR2CSA DBL4ϵ IgG | −.070 | −.48 to .34 | .739 |
| Cons- | 3.12 | .076 to 6.17 | .045 |
NOTE. CI, confidence interval.
H IgG antibody levels of individual plasma samples were recorded as the Median Fluorescent Intensity (MFI) using a multiplex bead-based assay.
*
Cons- (constant alpha) is the value that the dependent variable is predicted to have when all the independent variables (parameters) are equal to zero.