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. 2011 Mar 23;36(7):1518–1530. doi: 10.1038/npp.2011.37

Figure 5.

Figure 5

(a) Milnacipran (10 mg/kg) prevents ethanol self-administration reacquisition in dependent (n=8) rats but not in non-dependent rats (n=8). Extinction, responses during the final three extinction sessions; CS+ethanol priming, responses during presentation of an ethanol-associated conditioned stimulus. **P<0.01 and ***P<0.001 compared with respective extinction sessions; @@@P<0.001 compared with extinction; #P<0.05 compared with respective saline treatment. (b) Milnacipran (40 mg/kg) prevented ethanol self-administration reacquisition in dependent (n=12) and non-dependent (n=8) rats. **P<0.01 and ***P<0.001 compared with respective extinction sessions; ###P<0.001 compared with respective saline treatment.