Figure 3.

Toluene enhances both the frequency and amplitude of mIPSCs in PFC pyramidal neurons. (a) Representative example of GABA-mediated mIPSCs from a mPFC neuron before, during, and after washout of a 3 mM toluene solution. Summary plots below show the cumulative probability for the inter-event interval (b) and amplitude (c) of the same example recording. (d and e) Summary of effects of toluene on miniature IPSC frequency and amplitude. ^*Value significantly different from baseline (p<0.05; repeated measures ANOVA, post hoc Dunnett's multiple comparison test). Data are mean±SEM. The color reproduction of this figure available on the HTML full text version of the paper.