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. 2011 Mar 23;36(7):1531–1542. doi: 10.1038/npp.2011.38

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Copyright © 2011 American College of Neuropsychopharmacology

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Toluene affects spontaneous but not miniature EPSCs. (a) Representative examples of mEPSCs recorded before, during, or following exposure to 3 mM toluene. Panels below are from the same recording and show a cumulative probability chart of the inter-event interval (IEI, b) and amplitude (c) of mEPSCs. Summary of effects of 3 mM toluene on AMPA mEPSC frequency (d) and amplitude (e). Data are from six neurons. (f) Representative example of spontaneous AMPA-mediated EPSCs. Panels below show cumulative probability charts of IEI (g) and amplitude (h) from the same recording. Summary figure showing the effect of toluene on frequency (i) and amplitude (j). ^*Value significantly different from baseline (p<0.05, paired t-test). Data are mean±SEM. The color reproduction of this figure available on the HTML full text version of the paper.