Figure 2.
Representation of the interaction between autoantibodies and IRF5 and IRF7 genotype upon serum IFN-α levels in SLE patients. Bars on the graph represent median serum IFN-α levels in a group of SLE patients defined by the labels on the graph. “Risk” refers to subjects who carry IRF5 or IRF7 polymorphisms associated with SLE susceptibility in case-control studies, and “non-risk” refers to subjects who lack these variants.