Table 1.

Frequency of GNAQ Mutations in Benign and Malignant Neoplasms

Neoplasm type	GNAQ mutations	Citation
Uveal melanoma	46-49%	Onken et al, Van Raamsdonk et al
Mucosal melanoma	0%	Van Raamsdonk et al, Present study
Cutaneous melanoma (acral sites)	0%	Van Raamsdonk et al, Present study
Cutaneous melanoma (non-acral sites with chronic sun-induced damage)	0-4%	Van Raamsdonk et al, Present study
Blue nevus	46-83%	Lamba et al, Van Raamsdonk et al
Malignant blue nevus	50%	Van Raamsdonk et al
Nevus of Ota	6-46%	Lamba et al, Van Raamsdonk et al
Congenital nevus	0%	Van Raamsdonk et al
Deep penetrating nevus	0%	Van Raamsdonk et al
Spitz nevus	0%	Van Raamsdonk et al
Primary melanocytic neoplasms of the central nervous system	37%	Kusters-Vandevelde et al
Other neoplasms (carcinoma of the breast, colon, bladder, lung, ovarian, pancreas, thyroid; gastrointestinal stromal tumor; glioma; acute myelogenous leukemia)	0%	Lamba et al

ND, not determined