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Effects of perifosine on radiation-induced apoptosis and the G2/M checkpoint. A, CWR22RV1 cells were treated with perifosine (10 μM), radiation (6Gy, IR), or combination as indicated. Cellular apoptosis was detected by FACs. B. Quantititative analysis of the FACs data. C. CWR22RV1 cells were treated with control, radiation only (6Gy, IR), perifosine only (5 μM) or combination before they were subjected to the Western blot analysis using indicated antibodies.
