Table 4.
Controlling the effect of gene position.
| Gene length | Expression | Recombination | |
|---|---|---|---|
|
FOPAT N = 147193 codons R2 = 0.260*** P(GL)NS,P(Expr)***, P(dmc1, mre110)*** |
-0.0480NS | +0.3696*** | Co:-0.1064*** nCo:-0.0922*** spo11:-0.0442NS dmc1:-0.1224*** mre110:-0.0520* mre116:-0.0922*** |
|
FOPGC N = 180789 codons R2 = 0.445*** P(GL)NS, P(Expr)***, P(mre110)*, P(dmc1)*** |
-0.1289*** | +0.3839*** | Co:+3284*** nCo:+0.2472*** spo11:+0.3909*** dmc1:+0.4829*** mre110:+2648*** mre116:+0.2669*** |
|
FGCOpt N = 70401 codons R2 = 0.174*** P(GL)NS, P(Expr)NS P(dmc1, mre110)*** |
-0.0751** | +0.1216*** | Co:+0.2735*** nCo:+0.1843*** spo11:+0.3232*** dmc1:+0.3837*** mre110:+0.2104*** mre116:+0.2368*** |
|
FGCNon-Opt N = 126878 codons R2 = 0.224*** P(GL)NS, P(Expr)*** P(dmc1, mre110)*** |
-0.0481NS | +0.0410NS | Co:+0.2990*** nCo:+0.2339*** spo11:+0.3506*** dmc1:+0.4390*** mre110:+0.2311*** mre116:+0.2754*** |
Spearman Rank Correlations between frequencies of optimal and GC-ending codons with gene length, expression, and various recombination measures after controlling for a potential effect of gene position. The same 1571 genes were used for all measures. Presented are also MR results of variables whose log-transformation did not grossly deviate from a normal distribution. *P < 0.05, **P < 0.01,***P < 0.001