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. Author manuscript; available in PMC: 2011 May 18.
Published in final edited form as: J Immunol. 2011 Feb 4;186(6):3421–3431. doi: 10.4049/jimmunol.1000569

FIGURE 8.

FIGURE 8

Enrichment of NK cell numbers in the kidneys of MRL/lpr mice. A, Representative kidney sections stained with H&E from an MRL/mp mouse, a 9-wk-old MRL/lpr mouse, and a 21-wk-old MRL/lpr mouse. At the time of sacrifice, the kidneys were removed and sectioned before staining with H&E (original magnification ×100 [top row] and ×400 [bottom row]). Kidney MNCs were obtained from MRL/mp and predisease and diseased MRL/lpr mice. Absolute numbers of NK cells (B), CD226+ NK cells (C), B cells (E), and T cells (F) were calculated as detailed in Materials and Methods. Results are expressed as the number of cells per two kidneys. D, NK cells from kidney MNCs in MRL/mp and predisease and diseased MRL/lpr mice were assayed ex vivo for CD69 expression. Results are expressed as the mean ± SEM for each group. Significance was determined using one-way ANOVA, followed by the Bonferroni post hoc test.