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. Author manuscript; available in PMC: 2011 May 18.
Published in final edited form as: Cell Mol Bioeng. 2010 Dec;3(4):376–386. doi: 10.1007/s12195-010-0132-0

Fig. 1.

Fig. 1

The RANKL and OPG gene expression and RANKL/OPG ratio examined in rat primary osteoblasts after 6 or 12 h stimulation with stepwise increasing ( Inline graphic 5-10-15 dyn/cm2) or decreasing ( Inline graphic 15-10-5 dyn/cm2) FSS relative to static control (=1). The RANKL and OPG mRNA were normalized with β-actin. To indicate significant difference between pair comparison, the following symbals are used: * FSS vs the static control; # stepwise increasing FSS vs decreasing FSS for the same stimulation period (6 or 12h). There was no difference between 6 h and 12 h stimulation using either increasing or decreasing FSS.