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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Biomaterials. 2010 Oct 14;31(36):9373–9381. doi: 10.1016/j.biomaterials.2010.07.078

Figure 6. GIEMSA histology.

Figure 6

A) Representative sagittal control skull section showing GIEMSA staining in normal uninjured rat calvaria. B) Representative sagittal section from the sham group at 4 weeks, showing fusion of the bones on one side and incomplete fusion on the other. C) Representative sagittal skull section at 4 weeks from the adhesive group showing adhesive within and on the surface of the craniotomy. The adhesive was sufficient to maintain the placement of the craniotomy. Complete bone fusion was not observed on either side of the craniotomy. D) Representative sagittal section from the sham group at 12 weeks, showing fusion of the craniotomy on both sides. E) Representative sagittal skull section at 12 weeks from the adhesive group showing adhesive within and on the surface of the craniotomy. Bone fusion was achieved by 12 weeks. Sections are oriented with the side in contact with the dura down and the nose of the animal to the left. Adhesive appears black with GIEMSA staining. Zones of the craniotomy are shown in dashed lines. Scalebar = 500 μm.