Fig. 2.
Analysis of the importance of NRBE sequences in nPE2 enhancer activity in POMC hypothalamic neurons of transgenic mice. The two transgenes used are depicted above. Hypothalamic (Hyp) and pituitary (Pit) sections of representative postnatal day 1 founder transgenic mice carrying a transgene with wild-type NRBE or mutated NRBE sequences (*) show green fluorescence from EGFP expression. Arc: arcuate nucleus, AL: anterior lobe, IL: intermediate lobe.