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. 2011 May 18;6(5):e19566. doi: 10.1371/journal.pone.0019566

Table 1. Baseline characteristics of 253 tuberculosis patients by HIV status in a tertiary care hospital in Rwanda.

HIV positive HIV negative p-value
n = 167 n = 86
n (%) n (%)
Demographics
Age in years, median (IQR) 36 (30–42) 32 (24–36) 0.0004
Female sex 76 (45.5) 39 (45) ns
Married 77 (46) 32 (37) ns
No formal education 17 (10) 9 (10) ns
Unemployed or student 44 (26) 44 (51) <0.0001
Alcohol abuse 124 (73) 48 (56) 0.003
Smoking, active 63 (38) 21 (24) 0.033
Hospital admission 130 (78) 23 (27) <0.0001
Clinical
Body mass indexa, median (IQR) 17,9 (16,0–20,2) 18,9 (16,8–20,4) ns
Hemoglobin (g/dL), median (IQR) 9,9 (8,4–12) 13,1 (11,6–14,5) <0.0001
Site of TBb
 Pulmonary 54 (32) 48 (55) 0.001
 Extrapulmonary 77 (46) 31 (36)
 Pulmonary and extrapulmonary 36 (22) 7 (8)
Smear positivity (n = 144)c 39 (44) 39 (71) 0.002
Positive hepatitis B surface antigen (n = 135)d 6 (7) 1 (2) ns
Previous TB treatment 25 (15) 4 (5) 0.015
Fluconazole treatment e 32 (19) 0 (0) <0.0001
Traditional drugs e 12 (7) 7 (8) ns
Severe adverse event 58 (35) 6 (7) <0.0001
a

Body mass index is defined as the weight in kilograms divided by the square of the height in meters.

b

TB can affect multiples sites in one patient.

c

Smear-positivity from any biological specimen, including sputum, lymph node aspirate, etc.

d

Hepatitis B surface antigen positive in 6/87 hiv-infected and 1/48 hiv-uninfected persons.

e

within one week prior to admission.

p-value<0.05; IQR = interquartile range.