Table 4. Predictors of serious adverse events for 167 HIV-infected tuberculosis patients in univariate and multivariate analysis.
Variable | unadjusted HR | 95% CI | p-value | adjusted HR | 95% CI | p-value |
Age <35 years | 1.62 | 0.97–2.71 | ns | 1.41 | 0.83–2.40 | ns |
Female sex | 1.30 | 0.78–2.17 | ns | - | ||
Smoking | 0.91 | 0.53–1.55 | ns | - | ||
Alcohol intake | 0.78 | 0.44–1.37 | ns | - | ||
Hospital admission | 2.04 | 0.97–4.30 | ns | 1.44 | 0.65–3.19 | ns |
Extrapulmonary tuberculosis | 2.12 | 1.12–4.00 | 0.020 | 1.99 | 1.05–3.76 | 0.036 |
Prior tuberculosis history | 1.05 | 0.51–2.13 | ns | - | ||
Body mass index <18.5 kg/mm2 | 1.50 | 0.86–2.61 | ns | - | ||
Hemoglobin <11 g/dL | 1.40 | 0.80–2.45 | ns | - | ||
CD4 count <100 cells/mm3 | 1.71 | 1.01–2.90 | 0.044 | 1.55 | 0.90–2.70 | ns |
Use of antiretroviral treatment | 1.36 | 0.73–2.52 | ns | - |
HR: hazard ratio, Cox proportional hazard regression analysis; 95% CI: 95% confidence interval; p-value<0.05.