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Constitutive internalization of chimeric TGF-β receptors. Ligand-independent decrease of GM-CSF surface binding in the presence (closed symbols) or absence (open symbols) of 100 μM in wild-type chimeric A105 fibroblasts (□, ▪) and MB-18 epithelial cells (●, ○). Each point represents the mean (± SE) of three separate experiments done in duplicate.
