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. 2011 May 18;6(5):e19665. doi: 10.1371/journal.pone.0019665

Figure 2. Intraperitoneal injections of PEGLA reduced bone remodelling in mated and non-mated mice.

Figure 2

A & B. Representative Von Kossa stained tibial sections from mated (A) PEGylation reagent and (B) PEGLA treated mice show reduced trabecular bone (bone stains black). C–I. Tibial (C) trabecular bone volume (BV/TV), (D) trabecular thickness (TbTh), (E) trabecular number (TbN), (F) osteoid surface (OS/BS), (G) osteoblast surface (ObS/BS), (H) osteoclast surface (OcS/BS) and (I) osteoclast length (OcL). All values are mean ± SEM for 4–7 mice per group. *, significant difference (P<0.05) to PEGylation reagent controls of the same mating status; +, significant difference (P<0.05) to non-mated PEGylation reagent controls.